MED-2

WormBase ID: WBGene00003181

WormBase description: Is predicted to have DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Is involved in endodermal cell fate specification and pharynx development. Is expressed in E; EMS; MS; and gonad.

Reporter verification: Verified by PCR and sequencing
Primers used to verify fosmid reporter: 5'-ACTCCACCGAGCAATTCTGA-3'

Strain name: RW10479

Strain genotype: unc-119 (ed3) III; itIs37 (pie-1p::mCherry::H2B::pie-1 3'UTR + unc-119(+)); stIs10116 (his-72p::his-24::mCherry::let-858 3'UTR + unc-119(+)); stIs10426 (med-2::TGF(6.2B3)::GFP::TY1::3xFLAG)

Expression pattern: Lineage-specific, Transient-expression

Lineage expression pattern

350 stage

600 stage

3D expression pattern

4-cells

8-cells

15-cells

28-cells

~50-cells

~100-cells

~200-cells

~350-cells

~500-cells

~600-cells

600-cells

bean-stage

Inferred TF relationships

Based on expression similarity (strong, medium, weak): END-3, CEH-51, DPFF-1, CEH-39, PAL-1, REF-2, HMBX-1, SEL-8, NHR-10


Based on ChIP-seq (directly from ModERN database, targets from L1 stage ChIP-seq data are underlined)

Targeting: no-data

Targeted by: NA

Based on reannotated ChIP-seq (peaks are assigned to a target if it is located within 2 kb relative to the transcription start site; targets from L1 stage ChIP-seq data are underlined)

Targeting: no-data

Targeted by: NA