miniODP: a reusable framework for building multi-omics resources in understudied organisms
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Citation:
- Yang H, Wang Z, Shan Z, Shang H, Jiang P, Li Y, Tu Q. 2026. miniODP: a reusable framework for building multi-omics resources in understudied organisms. bioRxiv. doi:10.1101/2024.01.06.573815
Building multi-omics resources for understudied organisms requires assay selection, public-data curation, gene identifier handling, portal deployment, and visualization, yet these tasks are rarely packaged into a reusable framework. To fill this gap, we developed the mini Omics Data Portal (miniODP), which combines species pages, gene-centric modules, genome browsing, and sequence search with configuration files, species onboarding workflows, and demonstration data for self-deployment. Alongside the software, we propose miniENCODE core assays: a reduced RNA-seq, ATAC-seq, and H3K27ac profiling set for regulatory analysis. Current miniODP includes seven species, covering 3,568 bulk runs, 3.61 million cells, and 1,865 genome-browser tracks. We welcome collaborations with organism-specific communities interested in deploying miniODP on their own servers or hosting curated multi-omics datasets through our platform. Please contact us to discuss potential collaborations.
