HLH-11

WormBase ID: WBGene00001955

WormBase description: Is an ortholog of human TFAP4 (transcription factor AP-4). Is predicted to have DNA-binding transcription factor activity. Is expressed in excretory cell; male-specific anatomical entity; non-striated muscle; pharynx; and somatic nervous system.

Reporter verification: Verified by PCR and sequencing
Primers used to verify fosmid reporter: 5'-TTGCCATCAATTCCAGAAGC-3'

Strain name: SYS421

Cross: OP396 x JIM113

Strain genotype: ujIs113 (pie-1p::mCherry::H2B; nhr-2p::mCherry::his-24::let858 3'UTR; unc-119(+)) II; wgIs396 (hlh-11::TY1::EGFP::3xFLAG + unc-119(+))

Expression pattern: Not expressed

Lineage expression pattern

350 stage

600 stage

3D expression pattern

4-cells

8-cells

15-cells

28-cells

~50-cells

~100-cells

~200-cells

~350-cells

~500-cells

~600-cells

600-cells

bean-stage

Inferred TF relationships

Based on expression similarity (strong, medium, weak): NA


Based on ChIP-seq (directly from ModERN database, targets from L1 stage ChIP-seq data are underlined)

Targeting: no-data

Targeted by: BCL-11, CEH-14, CEH-18, CEH-31, CEH-34, CEH-6, DVE-1, ELT-2, ETS-4, HLH-1, HLH-30, HLH-8, K09A11.1, LIN-13, LSY-2, MEP-1, MLS-2, NFYA-1, RNT-1, SOX-4, SYD-9, TBX-2, UNC-120, UNC-42, UNC-55, UNC-62

Based on reannotated ChIP-seq (peaks are assigned to a target if it is located within 2 kb relative to the transcription start site; targets from L1 stage ChIP-seq data are underlined)

Targeting: no-data

Targeted by: CEH-18, ELT-2