WormBase ID: WBGene00017430 WormBase description: Is an ortholog of human BCL11A (BAF chromatin remodeling complex subunit BCL11A) and BCL11B (BAF chromatin remodeling complex subunit BCL11B). Is predicted to have nucleic acid binding activity. Is expressed in head; hypodermis; muscle cell; neurons; and pharynx. Human ortholog(s) of this gene are implicated in several diseases, including Duane-radial ray syndrome; IVIC syndrome; and Townes-Brocks syndrome. |
Reporter verification: Verified by PCR and sequencing |
Strain name: SYS581 Cross: OP471 x JIM113 Strain genotype: ujIs113 (pie-1p::mCherry::H2B; nhr-2p::mCherry::his-24::let858 3'UTR; unc-119(+)) II; wgIs471 (bcl-11::TY1::EGFP::3xFLAG(92C12) + unc-119(+)) |
Expression pattern: Not expressed |
Lineage expression pattern 350 stage   |
600 stage  |
3D expression pattern  4-cells  8-cells  15-cells  28-cells  ~50-cells  ~100-cells  ~200-cells  ~350-cells  ~500-cells  ~600-cells  600-cells  bean-stage |
Inferred TF relationships Based on expression similarity (strong, medium, weak): NA Based on ChIP-seq (directly from ModERN database, targets from L1 stage ChIP-seq data are underlined) Targeting: BLMP-1, CEBP-1, CEH-43, CRH-2, DAF-12, DAF-19, EGRH-1, ETS-5, FOS-1, HLH-11, HLH-30, K09A11.1, LAG-1, LIM-7, LIN-13, MDL-1, NHR-102, NHR-23, NHR-49, POP-1, RCOR-1, SDZ-38, SKN-1, SMA-2, SWSN-7, TBX-2, Y55F3AM.14, ZTF-6 Targeted by: BLMP-1, CEH-18, CEH-31, CEH-34, DMD-4, ELT-1, ELT-2, HAM-2, HLH-1, HLH-30, REF-2, RNT-1, SPTF-1, TBX-2, UNC-120, ZIP-8 |
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Targeting: BLMP-1, CEBP-1, CRH-2, DAF-19, ETS-5, HLH-30, LAG-1, LIN-13, MDL-1, NHR-23, NHR-49, POP-1, RCOR-1, SKN-1, SMA-2, SVH-5, SWSN-7, TBX-2 |
