AHA-1

WormBase ID: WBGene00000095

WormBase description: Is an ortholog of human ARNT (aryl hydrocarbon receptor nuclear translocator). Exhibits DNA binding activity; DNA-binding transcription factor activity; and RNA polymerase II transcription factor binding activity. Contributes to sequence-specific DNA binding activity. Is involved in several processes, including positive regulation of transcription by RNA polymerase II; social behavior; and transcription by RNA polymerase II. Localizes to RNA polymerase II transcription factor complex. Is expressed in hypodermis; intestine; neurons; and pharynx.

Reporter verification: Verified by PCR and sequencing
Primers used to verify fosmid reporter: 5'-ATTACCTGCTTTCAAGAGTGTGTGC-3'

Strain name: SYS135

Cross: OP124 x JIM113

Strain genotype: ujIs113 (pie-1p::mCherry::H2B; nhr-2p::mCherry::his-24::let858 3'UTR; unc-119(+)) II; wgIs124 (aha-1::TY1::EGFP::3xFLAG(92C12) + unc-119(+))

Expression pattern: Non-specific

Lineage expression pattern

350 stage

600 stage

3D expression pattern

4-cells

8-cells

15-cells

28-cells

~50-cells

~100-cells

~200-cells

~350-cells

~500-cells

~600-cells

600-cells

bean-stage

Inferred TF relationships

Based on expression similarity (strong, medium, weak): EGL-46, Y48G1C.6, NGN-1, TAB-1, MLS-2, EGL-44, CEBP-1


Based on ChIP-seq (directly from ModERN database, targets from L1 stage ChIP-seq data are underlined)

Targeting: CEBP-1, ATHP-1, CEH-38, EFL-1, FOS-1, HLH-11, HLH-30, MDL-1, MEF-2, MEP-1, SKN-1

Targeted by: PHA-4

Based on reannotated ChIP-seq (peaks are assigned to a target if it is located within 2 kb relative to the transcription start site; targets from L1 stage ChIP-seq data are underlined)

Targeting: CEBP-1, ATHP-1, CEH-5, DPL-1, EFL-1, HLH-30, MDL-1, MEF-2, MEP-1, SKN-1

Targeted by: MLS-2, CEH-83, ELT-3, PHA-4, UNC-42